BAX antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 5F4
Isotype: IgG2a
Immunogen: BCL2-associated X protein
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 21 kDa
Uniprot: Q07812
Gene id: 581
Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Field of research: Neuroscience, Cancer, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB,IHC,IF
Dilution: WB: 1:1000-1:10000; IHC: 1:400-1:1000; IF: 1:50-1:500
Target: BAX
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat
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Clonality: Monoclonal
Clone: 5F4
Isotype: IgG2a
Immunogen: BCL2-associated X protein
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 21 kDa
Uniprot: Q07812
Gene id: 581
Background: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Field of research: Neuroscience, Cancer, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB,IHC,IF
Dilution: WB: 1:1000-1:10000; IHC: 1:400-1:1000; IF: 1:50-1:500
Target: BAX
Purification: Protein A+G purification
Reactivity: Human, Mouse, Rat