B3GALNT2 antibody - 100 µg

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Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: beta-1,3-N-acetylgalactosaminyltransferase 2
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 55-60 kDa
Uniprot: Q8NCR0
Gene id: 148789
Background: Beta-1,3-N-acetylgalactosaminyltransferase that synthesizes a unique carbohydrate structure, GalNAc-beta-1-3GlcNAc, on N-and O-glycans. Has no galactose nor galactosaminyl transferase activity toward any acceptor substrate. Involved in alpha-dystroglycan(DAG1) glycosylation: acts coordinately with GTDC2
POMGnT2 to synthesize a GalNAc-beta3-GlcNAc-beta-terminus at the 4-position of protein O-mannose in the biosynthesis of the phosphorylated O-mannosyl trisaccharide(N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan, which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
Target: B3GALNT2
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat

222.50 € 222.5 EUR 222.50 € VAT Excluded

222.50 € VAT Excluded

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