ARL3 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: ADP-ribosylation factor-like 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 20 kDa
Uniprot: P36405
Gene id: 403
Background: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins(GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: ARL3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: ADP-ribosylation factor-like 3
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 20 kDa
Uniprot: P36405
Gene id: 403
Background: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors(GEF) and GTPase-activating proteins(GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins(GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IF
Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Target: ARL3
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat