ARHGEF7 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: Rho guanine nucleotide exchange factor(GEF) 7
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 70 kDa
Uniprot: Q14155
Gene id: 8874
Background: Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IP, WB
Dilution: WB: 1:1000-1:4000; IP: 1:500-1:2000
Target: ARHGEF7
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: Rho guanine nucleotide exchange factor(GEF) 7
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 70 kDa
Uniprot: Q14155
Gene id: 8874
Background: Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Field of research: Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, IP, WB
Dilution: WB: 1:1000-1:4000; IP: 1:500-1:2000
Target: ARHGEF7
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat