APEX1 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: APEX nuclease (multifunctional DNA repair enzyme) 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 39 kDa
Uniprot: P27695
Gene id: 328
Background: Apurinic
apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Field of research: Cardiovascular, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP, IF
Dilution: WB: 1:500 - 1:2000; IF: 1:50 - 1:100; IP: 1:50 - 1:200
Target: APEX1
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: APEX nuclease (multifunctional DNA repair enzyme) 1
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 39 kDa
Uniprot: P27695
Gene id: 328
Background: Apurinic
apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
Field of research: Cardiovascular, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP, IF
Dilution: WB: 1:500 - 1:2000; IF: 1:50 - 1:100; IP: 1:50 - 1:200
Target: APEX1
Purification: Immunogen affinity purified
Reactivity: Human