ANAPC5 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: anaphase promoting complex subunit 5
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 85 kDa
Uniprot: Q9UJX4
Gene id: 51433
Background: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex
cyclosome (APC
C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC
C and for the interaction of APC
C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Target: ANAPC5
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: anaphase promoting complex subunit 5
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 85 kDa
Uniprot: Q9UJX4
Gene id: 51433
Background: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex
cyclosome (APC
C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC
C and for the interaction of APC
C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
Field of research: Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Target: ANAPC5
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat