A2M antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: alpha-2-macroglobulin
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 185 kDa
Uniprot: P01023
Gene id: 2
Background: Alpha-2-macroglobulin, also known as α2-macroglobulin(α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease.
Field of research: Immunology, Cardiovascular, Metabolism, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:2000-1:20000; IP: 1:200-1:1000; IF: 1:50-1:500; IHC: 1:20-1:200
Target: A2M
Purification: Immunogen affinity purified
Reactivity: Human
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Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: alpha-2-macroglobulin
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 185 kDa
Uniprot: P01023
Gene id: 2
Background: Alpha-2-macroglobulin, also known as α2-macroglobulin(α2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even though A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease.
Field of research: Immunology, Cardiovascular, Metabolism, Signal Transduction
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:2000-1:20000; IP: 1:200-1:1000; IF: 1:50-1:500; IHC: 1:20-1:200
Target: A2M
Purification: Immunogen affinity purified
Reactivity: Human