AHR antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: aryl hydrocarbon receptor
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 105 kDa
Uniprot: P35869
Gene id: 196
Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL
BMAL1 heterodimer mediated transcriptional activation of PER1.
Field of research: Epigenetics, Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200
Target: AHR
Purification: Immunogen affinity purified
Reactivity: Human, Mouse
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: aryl hydrocarbon receptor
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 105 kDa
Uniprot: P35869
Gene id: 196
Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes(such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL
BMAL1 heterodimer mediated transcriptional activation of PER1.
Field of research: Epigenetics, Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC, IP
Dilution: WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200
Target: AHR
Purification: Immunogen affinity purified
Reactivity: Human, Mouse