ACAN antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: aggrecan
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 70 kDa, 250-260 kDa
Uniprot: P16112
Gene id:
Background: Aggrecan(ACAN), also named as CSPCP, AGC1 and MSK16, belongs to the aggrecan
versican proteoglycan family(also including versican, brevican and neurocan). It is a major component of extracellular matrix of cartilagenous tissues. A major function of aggrecan is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. This polyclonal antibody raised against 1-298aa of human aggrecan reveals a band of 70 kDa, which is consistent with the molecular weight of degradation product generated by proteolysis at the aggrecanase site(PMID: 7852317; 9337874).
Field of research: Stem Cells, Cardiovascular, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:1000; IHC: 1:20-1:200
Target: ACAN
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: aggrecan
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 70 kDa, 250-260 kDa
Uniprot: P16112
Gene id:
Background: Aggrecan(ACAN), also named as CSPCP, AGC1 and MSK16, belongs to the aggrecan
versican proteoglycan family(also including versican, brevican and neurocan). It is a major component of extracellular matrix of cartilagenous tissues. A major function of aggrecan is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. This polyclonal antibody raised against 1-298aa of human aggrecan reveals a band of 70 kDa, which is consistent with the molecular weight of degradation product generated by proteolysis at the aggrecanase site(PMID: 7852317; 9337874).
Field of research: Stem Cells, Cardiovascular, Metabolism, Developmental biology
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IHC
Dilution: WB: 1:500-1:1000; IHC: 1:20-1:200
Target: ACAN
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat