ADIPOQ antibody - 100 µg
Host : Mouse
Clonality: Monoclonal
Clone: 6E1
Isotype: IgG2a
Immunogen: adiponectin, C1Q and collagen domain containing
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 26 kDa
Uniprot: Q15848
Gene id: 9370
Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: ADIPOQ
Purification: Protein A+G purification
Reactivity: Human, Mouse
Clonality: Monoclonal
Clone: 6E1
Isotype: IgG2a
Immunogen: adiponectin, C1Q and collagen domain containing
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 26 kDa
Uniprot: Q15848
Gene id: 9370
Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB
Dilution: WB: 1:500-1:2000
Target: ADIPOQ
Purification: Protein A+G purification
Reactivity: Human, Mouse