ADCY6 antibody - 100 µg
Host : Rabbit
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: adenylate cyclase 6
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 131 kDa
Uniprot: O43306
Gene id: 112
Background: Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors(PubMed:17916776, PubMed:17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells(PubMed:17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion(By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function(By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol(PubMed:17916776). Contributes to bone cell responses to mechanical stimuli(By similarity).
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP
Dilution: WB: 1:200-1:2000; IP: 1:200-1:1000
Target: ADCY6
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat
Clonality: Polyclonal
Clone:
Isotype: IgG
Immunogen: adenylate cyclase 6
Purity: ≥95% as determined by SDS-PAGE
Form: Liquid
Molecular weight: 131 kDa
Uniprot: O43306
Gene id: 112
Background: Catalyzes the formation of the signaling molecule cAMP downstream of G protein-coupled receptors(PubMed:17916776, PubMed:17110384). Functions in signaling cascades downstream of beta-adrenergic receptors in the heart and in vascular smooth muscle cells(PubMed:17916776). Functions in signaling cascades downstream of the vasopressin receptor in the kidney and has a role in renal water reabsorption. Functions in signaling cascades downstream of PTH1R and plays a role in regulating renal phosphate excretion. Functions in signaling cascades downstream of the VIP and SCT receptors in pancreas and contributes to the regulation of pancreatic amylase and fluid secretion(By similarity). Signaling mediates cAMP-dependent activation of protein kinase PKA. This promotes increased phosphorylation of various proteins, including AKT. Plays a role in regulating cardiac sarcoplasmic reticulum Ca(2+) uptake and storage, and is required for normal heart ventricular contractibility. May contribute to normal heart function(By similarity). Mediates vasodilatation after activation of beta-adrenergic receptors by isoproterenol(PubMed:17916776). Contributes to bone cell responses to mechanical stimuli(By similarity).
Field of research: Signal Transduction, Metabolism
Storage conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze
thaw cycles.)
Applications: ELISA, WB, IP
Dilution: WB: 1:200-1:2000; IP: 1:200-1:1000
Target: ADCY6
Purification: Immunogen affinity purified
Reactivity: Human, Mouse, Rat